Features of NSAIDs' use in pandemic. Gastroenterologist's view
نویسندگان
چکیده
Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat acute and chronic pain associated primarily with inflammatory changes. This group of is widely in neurology, rheumatology, traumatology, etc. The main mechanism action the effect on cyclooxygenase-2 (COX-2) blockade synthesis pro-inflammatory prostaglandins (PG), as well COX-1 suppression cytoprotective PG, which determines possibility side effects from gastrointestinal tract. In pandemic, use this has increased many times over. Features clinical course both viral infection itself other leads a significant change pharmacodynamics pharmacokinetics NSAIDs, may lead development undesirable effects.
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ژورنال
عنوان ژورنال: Medicinskij alfavit
سال: 2021
ISSN: ['2078-5631']
DOI: https://doi.org/10.33667/2078-5631-2021-6-32-34